The zombies and giant mutated monsters are definitely the highlights of the Resident Evil series. They range from small and fast to massive and intense. They're easily the best enemies to contend with throughout the entire franchise.
What about the villains? Almost every Resident Evil game has featured a main antagonist acting as a mastermind or pawn. This is where it's usually the flip of a coin: either the villain is a standout character in the series or they are laughably over the top. Which villains make gamers shiver with fear? Which ones force people to find some cheese to go with the ham they dish out?
10 Hilarious: Carla Radames (Resident Evil 6)
Resident Evil 6 is a contender for the worst game in the series. The monsters and villains alike had simply lost their touch, with the worst of them all being Carla Radames.
The idea of this character is not bad, but her execution is another story. Carla Radames being a perfect clone of Ada Wong just comes off as goofy. Under the right circumstances, this should have been a more tragic villain but instead, gamers just facepalmed at Carla.
9 Scary: Eveline (Resident Evil 7: Biohazard)
It is easy to instantly call Eveline a Resident Evil-ripoff of Alma from the F.E.A.R. games. With her white dress, long black hair, and mysterious powers, Eveline seemed like a weird villain for Resident Evil VII: Biohazard.
However, as Eveline's story unfolds and twists take place, the scarier she gets. The character even gets a good jumpscare here and there. Without spoilers, Eveline's story leads to a genuinely good twist and a memorable boss encounter.
8 Hilarious: Lucas Baker (Resident Evil 7: Biohazard)
There's a lot of craziness happening in Resident Evil 7 but even with that in mind, Lucas is just a strange villain. He never becomes a monster like the other members of the Baker family and his whole subplot feels like a leftover from the Saw movies.
Every time Lucas appears to threaten Ethan or force a new puzzle, it brings flashbacks to Riddler from the Arkham games. Lucas's antics are tedious and annoying. However, he can at least provide some laughs because of how over the top he can get.
7 Scary: William Birkin (Resident Evil 2)
An egotist to the very end, Birkin is one of the main culprits behind the T-Virus and the main scientist behind the G-Virus. His ego led to Wesker betraying him and leading S.T.A.R.S. to discover what the Umbrella Corporation was up to.
Later on, William is killed but only to mutate into a savage beast who would infect and kill his own family. While the tragedy goes more toward his wife and child, William is just an evil scientist that is satisfying to fight. His mutated form is nightmare fuel and would be one of the first B.O.W.s of the series.
6 Hilarious: B.O.W. Albert Wesker (Resident Evil 5)
Talk about ruining such a great villain. Albert Wesker is a genuinely great villain with a lot of charisma and devious acts to make someone love to hate him. Throughout Resident Evil 5, he remains a great elusive villain until the final act.
In the climax, Wesker transforms into a B.O.W. for the final boss fight and it is absolutely ridiculous. B.O.W. Wesker feels more like a supervillain from a Marvel game, not an action-horror title like Resident Evil.
5 Scary: Jack Baker (Resident Evil 7: Biohazard)
The father of the Baker family, Jack is the villain who chases Ethan the most in Resident Evil 7. In many ways, Jack is the spiritual successor to Mr. X since he breaks through walls like paper and takes more bullets than any of the monsters.
Unlike Mr. X, Jack is definitely not an unemotional machine. Jack is constantly taunting the player and is just over the top enough to convey the madness while still being scary. The boss fights with his monstrous forms are some of the best in the series!
4 Hilarious: Ramon Salazar (Resident Evil 4)
Resident Evil 4 is arguably the best game in the series; it's almost perfect. Emphasis on ALMOST perfect. So what's holding it back? The villain: Ramon Salazar. How did this villain make it passed anybody at Capcom? Did nobody look at this character and ask why they created a cartoon character?
Salazar's voice is beyond grating, he is not scary, and he looks like a twelve-year-old trying to cosplay Christopher Columbus. The only redeeming factor about the villain is that his mutated boss fight is genuinely challenging.
3 Scary: Marguerite Baker (Resident Evil 7: Biohazard)
At first, Mommy Dearest doesn't come across as all that scary. Creepy with a strange obsession with bugs? Sure, but never all that scary. However, the game decides to ditch terror for disturbing when Marguerite's final form comes into play.
With maggots, puss, and bugs excreting from her nether region, long neck, long arms and legs, and inhuman speed, Marguerite's entire boss fight is gross, disturbing, and shocking. David Cronenberg should be proud of Capcom for this one.
2 Hilarious: James Marcus (Resident Evil 0)
How did this happen? This villain, not for one second, looks like he belongs anywhere near this series. Up until this point, Resident Evil 0 was still the same grounded reality as the first game. Out of nowhere, a long-haired man in a dress shows up with opera music playing.
James Marcus more resembles a character from Final Fantasy. Be it his design, acting, or boss fight, nothing about the character works. It leads to something that is so bad, it is genuinely hilarious to see.
1 Scary: Mr. X (Resident Evil 2)
It was a difficult choice between Mr. X and Nemesis. Both Tyrants are great antagonists but in the end, Nemesis is not so much scary but intense. Mr. X on the other hand instills more fear in the player.
At any second, Mr. X could pop right through the wall or be around the corner. His footsteps can be heard; just knowing that he's after the player is more terrifying than just a hulking monster like Nemesis.
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